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- IHC0296M
- 2025年10月15日
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- 规格：
50T
| 产品编号 | IHC0296M |
| 英文名称 | Mouse SOX10 Ready-To-Use IHC Kit |
| 中文名称 | 小鼠转录因子SOX10即用型免疫组化试剂盒 |
| 英文别名 | DOM; PCWH; SOX10; WS2E; WS4; WS4C; Transcription factor SOX-10 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 亚基 | Monomer. Interacts with ARMCX3 at the mitochondrial outer membrane surface. Interacts with PAX3 (PubMed:21965087). |
| 亚细胞定位 | Cytoplasm Membrane Mitochondrion Mitochondrion outer membrane Nucleus |
| 组织特异性 | Expressed in fetal brain and in adult brain, heart, small intestine and colon. |
| 功能 | Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity). |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded mouse brain tissue slide using IHC0296M (Mouse SOX10 IHC Kit).
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Mouse SOX10 Ready-To-Use IHC Kit(IHC0296M)-50T
￥3200
