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- IHC0290M
- 2025年10月15日
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50T
| 产品编号 | IHC0290M |
| 英文名称 | Mouse CNN1 Ready-To-Use IHC Kit |
| 中文名称 | 小鼠钙调节蛋白-1即用型免疫组化试剂盒 |
| 英文别名 | CN; CNN1; CnnI; HEL-S-14; Sm-Calp; SMCC; calponin-1 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 亚基 | Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1. |
| 亚细胞定位 | actin cytoskeleton cytoskeleton focal adhesion |
| 组织特异性 | Smooth muscle, and tissues containing significant amounts of smooth muscle. |
| 相似性 | Belongs to the calponin family. |
| 功能 | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded mouse bladder tissue slide using IHC0290M (Mouse CNN1 IHC Kit).
Immunohistochemical analysis of paraffin embedded mouse stomach tissue slide using IHC0290M (Mouse CNN1 IHC Kit).
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Mouse CNN1 Ready-To-Use IHC Kit(IHC0290M)-50T
￥3200
