Rat NeuN Ready-To-Use IHC Kit(IHC0181R)-50T

Rat NeuN Ready-To-Use IHC Kit(

IHC0181R)-50T
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  • ¥3200
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  • IHC0181R
  • 2025年10月15日
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      50T

    产品编号 IHC0181R
    英文名称 Rat NeuN Ready-To-Use IHC Kit
    中文名称 大鼠神经元核抗原即用型免疫组化试剂盒
    英文别名 cDNA FLJ56884; FLJ56884; FLJ58356; FOX3; hCG_1776007; Homo sapiens (Human); HRNBP3; NeuN; RBFOX3; D11Bwg0517e; FOX-3; HRNBP3; NEUN; Neuna60; RGD1560070
    产品应用 IHC-P

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Rat
    保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
    注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 Fox-3, also known as NEUN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein that contains one RRM (RNA recognition motif) domain. Localized to both the nucleus and cytoplasm, Fox-3 is suggested to regulate alternative splicing events. Fox-3 is encoded by a gene located on human chromosome 17, which is comprised over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and LiFraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

     

    应用 推荐稀释比例

     

    Immunohistochemical analysis of paraffin embedded rat cerebellum tissue slide using IHC0181R (Rat NeuN IHC Kit).

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