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- D61168
- 2025年10月17日
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100mg
| 产品编号 | D61168 |
| 英文名称 | Imipramine hydrochloride |
| 中文名称 | 盐酸丙咪嗪 |
| 英文别名 | Imipramine (hydrochloride); Imipramine HCl; G 22355; Tofranil; Melipramine |
| 理论分子量 | 316.87 |
| 保存条件 | -20℃ |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects |
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文献和实验Protein Folding Liquid Chromatography
A method for carrying out protein folding with simultaneous separation by protein folding liquid chromatography (PFLC) is described herein. Furthermore, a two-dimensional chromatographic column, termed a 2D column, which can be independently
Purification of Antibodies Using Protein A-Sepharose and FPLC
1. Protein A has been expressed in recombinant form, and its crystal structure has been solved (4 ). The affinity of protein A for Fc regions is very high (K d = 10−7 ). The molecule contains four binding sites, but only two Fc domains can be bound
(1) 抗精神病作用 对以精神运动性兴奋和幻觉妄想为主的Ⅰ型精神分裂症疗效较好，亦用于治疗躁狂症。可迅速控制兴奋、躁动，继续用药，可使病人恢复理智、情绪安定、生活自理。作用机制与阻断中脑―边缘叶及中脑―皮质通路中的多巴胺 D 2 受体有关。 (2) 镇吐作用 对多种疾病和药物引起的呕吐都有效，系阻断催吐化学感受区（ CTZ ）的 D 2 受体所致。大剂量则直接抑制呕吐中枢。但对刺激前庭引起的呕吐无效。 (3) 对体温调节的影响 抑制体温调节中枢，使体温调节失灵，体温
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