- ￥2800
- Proteintech
- CL594-67220
- 2025年10月13日
- IF-P
- Mouse
- Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human LAIR1 protein
- 亚型：
IgG2a
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite®594 Fluorescent Dye
- 适应物种：
Human
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Mouse
- 应用范围：
IF-P
- 靶点：
LAIR1
- 抗体英文名：
CoraLite®594-conjugated LAIR1 Monoclonal antibody
- 抗体名：
CoraLite®594-conjugated LAIR1 Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF-P detected in | human tonsillitis tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-67220 targets LAIR1 in IF-P applications and shows reactivity with Human samples.
| 经测试应用 | IF-P |
| 经测试反应性 | Human |
| 免疫原 |
CatNo: Ag14459 Product name: Recombinant human LAIR1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 184-287 aa of BC027899 Sequence: FCLHRQNQIKQGPPRSKDEEQKPQQRPDLAVDVLERTADKATVNGLPEKDRETDTSALAAGSSQEVTYAQLDHWALTQRTARAVSPQSTKPMAESITYAAVARH |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | leukocyte-associated immunoglobulin-like receptor 1 |
| 别名 | CD305, hLAIR1, LAIR 1, LAIR1 |
| 计算分子量 | 287 aa, 31 kDa |
| GenBank蛋白编号 | BC027899 |
| 基因名称 | LAIR1 |
| Gene ID (NCBI) | 3903 |
| RRID | AB_2920100 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q6GTX8 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is a transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory motifs (PMID: 9285412). LAIR1 is expressed on the majority of human PBMCs, including NK, T, B, monocytes, and dendritic cells, as well as the majority of thymocytes (PMID: 10229813). It functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of NK cells, B cells and T cells. LAIR1 is a collagen receptor (PMID: 16754721). Tumor-expressed collagens can modulate immune cell function through the inhibitory collagen receptor LAIR1 (PMID: 21955987).
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