Anti-hnRNP U/p120 antibody [3G

This supplementary information is collated from multiple sources and compiled automatically. Heterogeneous nuclear ribonucleoprotein U (hnRNP U) also known as p120 is a multifunctional protein involved in various cellular processes. This protein has an approximate molecular mass of 120 kDa. It is expressed widely in different tissues predominantly within the nuclear compartment of cells. HnRNP U functions mainly in relation to RNA binding and regulation including alternative splicing RNA stability and RNA transport. Its ability to interact with both RNA and DNA attributes to a role in chromatin structure regulation and transcriptional control. Biological function summary HnRNP U plays a significant role in organizing chromatin architecture and facilitating transcription regulation. It often associates with other hnRNPs to form ribonucleoprotein complexes which are central in RNA metabolism. Importantly hnRNP U's capacity to interact with chromatin allows it to participate in chromatin remodeling which is necessary for processes such as embryonic development and cellular differentiation. It modifies the transcriptional landscape by influencing the accessibility of transcription factors to their DNA targets.