Anti-ERAB antibody [5F3]

This supplementary information is collated from multiple sources and compiled automatically. ERAB also known as 17-beta-hydroxysteroid dehydrogenase type 10 (HSD10) or 3-hydroxyacyl-CoA dehydrogenase type II is a multifunctional mitochondrial enzyme. It has a molecular mass of approximately 27 kDa. This enzyme is expressed in various tissues with high expression in the liver kidney heart and brain. ERAB plays a role in several metabolic processes thanks to its ability to catalyze reactions involving the oxidation of hydroxyacyl-CoA to ketoacyl-CoA derivatives alongside other substrates like steroids. Biological function summary The function of this enzyme extends beyond its metabolic activities. ERAB is part of the mitochondrial enzyme complex responsible for fatty acid oxidation and energy production. This places it centrally in cellular energy homeostasis. Additionally ERAB participates in the metabolism of neurosteroids which impacts brain function. Through its interactions ERAB influences signaling pathways by modulating local steroid concentrations in the nervous system affecting cellular communication and response.