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- Bioss
- bs-1031P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1031P |
| 英文名称 | IFITM1 Antibody Blocking Peptide |
| 中文名称 | 干扰素诱导跨膜蛋白1封闭多肽 |
| 英文别名 | CD225; CD225 antigen; CD 225; CD-225; IFI17; Interferon induced protein 17; Interferon induced transmembrane protein 1; Interferon inducible protein 9-27; Interferon-induced protein 17; Interferon-induced transmembrane protein 1; Interferon-inducible protein 9-27; Leu 13 antigen; Leu-13 antigen; LEU13; IFM1_HUMAN; Dispanin subfamily A member 2a; DSPA2a. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors > p53 pathway Cancer > Tumor biomarkers Immunology > Innate Immunity > Cytokines > Interferons Signal Transduction > Adapters > Transmembrane Stem Cells > Signaling Pathways > TGF beta > Interferon gamma Stem Cells > Signaling Pathways > Wnt > Surface Molecules |
| 亚基 | Interacts with CAV1; this interaction enhances the ability of CAV1 in inhibiting ERK activation. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 翻译后修饰 | Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus. |
| 相似性 | Belongs to the CD225 family. |
| 功能 | IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | IFITM1 expression is induced by interferons alpha and gamma and it is thought to play a role in control of cell growth. It is upregulated in several tumor types and may be useful as a tumor biomarker. |
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IFITM1 Antibody Blocking Peptide(bs-1031P)-500ug
￥880
