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- Bioss
- bs-16153R-Bio
- 2026年10月17日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-16153R-Bio |
| 英文名称 | FMO2 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的肝黄素单加氧酶2抗体 |
| 英文别名 | 2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N oxide forming] 2; Dimethylaniline monooxygenase [N-oxide-forming] 2; Dimethylaniline oxidase 2; Flavin containing monooxygenase 2(non functional); Flavin containing monooxygenase 2; FLJ40826; FMO 1B1; FMO 2; FMO; FMO pulmonary; FMO1B1; FMO2; FMO2_HUMAN; MGC28212; OTTMUSP00000028686; OTTMUSP00000028687; Pulmonary flavin containing monooxygenase 2; Pulmonary flavin-containing monooxygenase 2. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, ELISA=1:5000-10000, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FMO2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Microsome membrane. Endoplasmic reticulum membrane. |
| 组织特异性 | Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. |
| 翻译后修饰 | The truncated form is probably unable to fold correctly and is rapidly degraded._x000D_ FMO2*1 is sumoylated at 'Lys-492'. |
| 相似性 | Belongs to the FMO family. |
| 功能 | Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in some human populations, this enzyme is truncated and likely degraded rapidly. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq, Jun 2013] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
| {IF} | {1:100-500} |
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FMO2 Rabbit pAb, Biotin conj.(bs-16153R-Bio)-100ul
￥2980
