- ￥2980
- Bioss
- bs-1045R-FITC
- 2025年10月15日
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100ul
| 产品编号 | bs-1045R-FITC |
| 英文名称 | CCL3 Rabbit pAb, FITC conjugated |
| 中文名称 | FITC标记的巨噬细胞炎症因子1α抗体 |
| 英文别名 | Tonsillar lymphocyte LD78 alpha protein; CCL 3; CCL3; Chemokine C C motif ligand 3; Chemokine CC Motif Ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein antibody L2G25B; LD78ALPHA; Macrophage inflammatory protein 1 alpha; MIP 1 alpha; MIP-1 alpha; MIP 1A; MIP1A; PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; Small inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; CCL3_HUMAN; |
| 中文别名 | MIP-1α; MIP-1-α; MIP 1 α; MIP1α; MIP1-α. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MIP-1 alpha |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Immune System Diseases > Antiviral Signaling > HIV-related Immunology > Innate Immunity > Chemokines > Beta Chemokines (CC) Immunology > Innate Immunity > Macrophage / Inflamm. Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Blood cell antigens ELISA kits |
| 亚基 | Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in lung, spleen, and pancreas. |
| 翻译后修饰 | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
| 相似性 | Belongs to the intercrine beta (chemokine CC) family. |
| 功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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CCL3 Rabbit pAb, FITC conjugated(bs-1045R-FITC)-100ul
￥2980
