OIP-5/CT86 Rabbit pAb, HRP conjugated(bs-8856R-HRP)-100ul

OIP-5/CT86 Rabbit pAb, HRP con

jugated(bs-8856R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-8856R-HRP
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-8856R-HRP
    英文名称OIP-5/CT86 Rabbit pAb, HRP conjugated
    中文名称HRP标记的癌/睾丸抗原抗体86抗体
    英文别名5730547N13Rik; Cancer/testis antigen 86; CT 86; CT86; hMIS18beta; LAP2alpha interactor 25; LINT 25; LINT25; MIS18B; MIS18beta; MS18B_HUMAN; OIP 5; OIP-5; OIP5; Opa interacting protein 5; Opa-interacting protein 5; Protein Mis18-beta.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human OIP-5
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
    功能Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料OIP5 is a 229 amino acid nuclear protein that is required for chromosome segregation during mitosis. OIP5 exists as a homodimer but can also heterodimerize with FASP1 (FAPP1-associated protein 1). Essential for the recruitment of CENP-A (centromere autoantigen A) to centromeres, OIP5 localizes to centromeres of interphase cells during late anaphase and G1. The gene encoding OIP5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ELISA}{1:5000-10000}

     

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