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产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-14045R-PerCP-Cy7 |
| 英文名称 | CRB1 Rabbit pAb, PerCP-Cy7 conjugated |
| 中文名称 | PerCP-Cy7标记的CRB1蛋白抗体 |
| 英文别名 | CRB1; CRUM1_HUMAN; Protein crumbs homolog 1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CRB1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Sensory System > Visual system |
| 亚细胞定位 | Secreted and Apical cell membrane. Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina. |
| 组织特异性 | Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. |
| 翻译后修饰 | Extensively glycosylated. |
| 相似性 | Belongs to the Crumbs protein family. _x000D_ Contains 19 EGF-like domains. _x000D_ Contains 3 laminin G-like domains. |
| 功能 | Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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CRB1 Rabbit pAb, PerCP-Cy7 conjugated(bs-14045R-PerCP-Cy7)-100ul
¥2980





