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- bs-14046R-PerCP
- 2025年09月30日
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100ul
| 产品编号 | bs-14046R-PerCP |
| 英文名称 | CRB2 Rabbit pAb, PerCP conjugated |
| 中文名称 | PerCP标记的CRB2蛋白抗体 |
| 英文别名 | Crb2; CRUM2_HUMAN; Crumbs homolog 2(Drosophila); Crumbs homolog 2; Crumbs-like protein 2; RP11-230L22.2. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CRB2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚细胞定位 | Secreted and Cell membrane. |
| 组织特异性 | Expressed in retina, fetal eye and brain. Also expressed in kidney, ARPE-19 and RPE/choroid cell lines, and at low levels in lung, placenta, and heart. |
| 相似性 | Belongs to the Crumbs protein family. _x000D_ Contains 15 EGF-like domains. _x000D_ Contains 3 laminin G-like domains. |
| 功能 | May play a role in polarized cells morphogenesis. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | CRB2 is a 1,285 amino acid protein that contains three laminin G-like domains and 15 EGF-like domains and exists as multiple alternatively spliced isoforms that are either secreted or membrane bound. Expressed in kidney and retina, as well as in fetal eye and brain, CRB2 is thought to play a role in the morphogenesis of polarized cells and may be involved in DNA repair. Defects in the gene encoding CRB2 are associated with the pathogenesis of autosomal recessive retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA), the former of which refers to a group of diseases that lead to the degeneration of retinal photoreceptor cells, ultimately resulting in a loss of vision. The gene encoding CRB2 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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CRB2 Rabbit pAb, PerCP conjugated(bs-14046R-PerCP)-100ul
￥2980
