- ￥2980
- Bioss
- bs-13092R-BF555
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
phospho-FAK (Y397) Recombinant Rabbit mAb(bsm-63137R)-25ul/50ul/100ul
￥800
Lamin B Receptor Rabbit pAb, BF488 conjugated(bs-5081R-BF488)-100ul
￥2980phospho-CD130/gp130 (Ser782) Rabbit pAb, PE conjugated(bs-10122R-PE)-100ul
￥2980
epsilon Tubulin Rabbit pAb, AP conjugated(bs-14617R-AP)-100ul
￥2980
phospho-Tyk2 (Tyr1054 + Tyr1055) Rabbit pAb, RBITC conjugated(bs-3437R-RBITC)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-13092R-BF555 |
| 英文名称 | phospho-ERBB3 (Tyr1276) Rabbit pAb, BF555 conjugated |
| 中文名称 | BF555标记的磷酸化HER3抗体 |
| 英文别名 | Her3/ErbB3(phospho-Tyr1276); p-HRE3(Tyr1276); ErbB 3(phospho Y1276); Receptor tyrosine-protein kinase erbB-3; ErbB-3; c erbB 3; c-erbB3; ErbB 3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor receptor; HER 3; HER3; LCCS2; MDA BF 1; MGC88033; p180 ErbB3; p45 sErbB3; p85 sErbB3; proto-oncogene-; receptor tyrosine protein kinase ERB3 [precursor]; Receptor tyrosine protein kinase erbB 3; Receptor tyrosine protein kinase erbB3; Tyrosine kinase type cell surface receptor HER3; V erb b2 avian erythroblastic leukemia viral oncogene homolog 3; v erb b2 erythroblastic leukemia viral oncogene homolog 3(avian); v erb b2 erythroblastic leukemia viral oncogene homolog 3; ERBB3_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human HER3 around the phosphorylation site of Tyr1289 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Growth factors > EGF Cancer > Oncoproteins/suppressors > Oncoproteins > Growth factor receptors Cancer > Tumor biomarkers > Oncoproteins Signal Transduction > Growth Factors/Hormones > EGF Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases Signal Transduction > Signaling Pathway > G Protein Signaling > Heterotrimeric G Proteins > G Proteins |
| 亚基 | Monomer and homodimer. Heterodimer with each of the other ERBB receptors (Potential). Interacts with CSPG5, PA2G4, GRB7 and MUC1. |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I. membrane protein. Isoform 2: Secreted. |
| 组织特异性 | Epithelial tissues and brain. |
| 翻译后修饰 | Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. Subject to autophosphorylation. |
| 相似性 | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. Contains 1 protein kinase domain. |
| 功能 | Binds and is activated by neuregulins and NTAK. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
phospho-ERBB3 (Tyr1276) Rabbit pAb, BF555 conjugated(bs-13092R-BF555)-100ul
￥2980
