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- Bioss
- bs-13599R-BF488
- 2025年09月30日
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100ul
| 产品编号 | bs-13599R-BF488 |
| 英文名称 | HoxC13 Rabbit pAb, BF488 conjugated |
| 中文名称 | BF488标记的同源盒蛋白HOX13抗体 |
| 英文别名 | ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-C13; Hox-3G; HOX3; HOX3G; HOXC13; HXC13; NUP98. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HoxC13 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > HOX Stem Cells > Embryonic Stem Cells > Intracellular |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain._x000D_ |
| 功能 | HOXC13 is a member of a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms and provide cells with specific positional identities on the anterior-posterior axis. HOXC13 is a sequence-specific transcription factor that may play a role in the development of hair, nail, and filiform papilla. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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HoxC13 Rabbit pAb, BF488 conjugated(bs-13599R-BF488)-100ul
￥2980
