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- 详细信息
- 技术资料
- 应用范围:
产品信息以Bioss网站为准
- 规格:
25T/50T/100T
| 规格: | 25T | 产品价格: | ¥220.0 |
|---|---|---|---|
| 规格: | 50T | 产品价格: | ¥360.0 |
| 规格: | 100T | 产品价格: | ¥580.0 |
| 产品编号 | bsm-30092M-BF488 |
| 英文名称 | human CD3 Mouse mAb, BF488 conjugated |
| 中文名称 | BF488标记的小鼠抗人CD3单克隆抗体 |
| 英文别名 | CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide(TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon(CD3 TCR complex); CD3e molecule, epsilon(CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD3 |
| 亚型 | Mouse IgG2a, k |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Adaptive Immunity > T Cells > CD Signal Transduction > Antibodies > cd3 Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative |
| 亚基 | he TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Contains 1 Ig-like (immunoglobulin-like) domain. Contains 1 ITAM domain. |
| 功能 | The CD3 complex mediates signal transduction. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |

scatter diagram showing peripheral blood lymphocytes stained with bsm-30092M-BF488. The cells were incubated with the antibody (bsm-30092M-BF488, 10µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
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human CD3 Mouse mAb, BF488 conjugated(bsm-30092M-BF488)-25T/50T/100T
¥220 - 580





