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- bs-20303R-BF488
- 2025年09月30日
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100ul
| 产品编号 | bs-20303R-BF488 |
| 英文名称 | HAP1 Rabbit pAb, BF488 conjugated |
| 中文名称 | BF488标记的舞蹈症相关蛋白1抗体 |
| 英文别名 | Huntingtin Associated Protein 1; HAP 1; HAP 2; HAP2; HAP-1; Hap1; HAP1_HUMAN; HAPP; hHAP1; hHLP1; HIP 5; HIP5; HLP; HLP1; Huntingtin-associated protein 1; huntingtin-associated protein 2; Neuroan 1; Neuroan1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HAP1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease > Huntington's disease Neuroscience > Neurology process > Neurogenesis Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 组织特异性 | Predominantly expressed in brain. Selectively expressed in neurons. |
| 相似性 | Contains 1 HAP1 N-terminal domain. |
| 功能 | Associates specifically with huntingtin. This binding is enhanced by an expanded polyglutamine repeat. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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HAP1 Rabbit pAb, BF488 conjugated(bs-20303R-BF488)-100ul
￥2980
