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- bs-5755R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-5755R-HRP |
| 英文名称 | Nucleoprotein TPR Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的核蛋白易位启动子区域TPR抗体 |
| 英文别名 | tpr; TPR_HUMAN; translocated promoter region(to activated MET oncogene); TPR_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Nucleoprotein TPR |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Kinases/phosphatases Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Signal Transduction > Protein Trafficking > Nuclear Import / Export |
| 亚基 | Interacts with MAD1L1 and MAD2L1. |
| 亚细胞定位 | Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore. Note=The assembly of the NPC is a stepwise process in which Trp-containing peripheral structures assemble after other components, including p62. Detected at kinetochores during prometaphase. |
| 组织特异性 | Highest in testis, lung, thymus, spleen and brain, lower levels in heart, liver and kidney. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 功能 | Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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Nucleoprotein TPR Rabbit pAb, HRP conjugated(bs-5755R-HRP)-100ul
￥2980
