- ￥2980
- Bioss
- bs-13751R-BF555
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
LINGO4 Rabbit pAb, BF488 conjugated(bs-11873R-BF488)-100ul
￥2980
Gamma Synuclein Rabbit pAb, FITC conjugated(bs-0622R-FITC)-100ul
￥2980
phospho-EGFR (Tyr998) Rabbit pAb, BF488 conjugated(bs-3112R-BF488)-100ul
￥2980Perilipin 1 Rabbit pAb, PE-Cy5.5 conjugated(bs-10779R-PE-Cy5.5)-100ul
￥2980
DEPDC1 Rabbit pAb, Pacific Blue conjugated(bs-6525R-PacificBlue)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-13751R-BF555 |
| 英文名称 | Claudin 17 Rabbit pAb, BF555 conjugated |
| 中文名称 | BF555标记的紧密连接蛋白17抗体 |
| 英文别名 | CLDN17; CLD17_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Claudin 17 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Tight Junctions |
| 亚细胞定位 | Integral membrane protein. Tight junctions. |
| 相似性 | Belongs to the claudin family. |
| 功能 | Claudin proteins are a family of transmembrane proteins associated with tight junctions, and different tissues exhibit different Claudin composition. There are 18 homolgs present in humans, and mutations in any of these proteins cause a variety of human disease, this indicates their physiological importance. CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules (JAMs). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Mammalian claudin-17 and claudin-8 may be the result of a gene duplication. Claudin-17 is expressed in stratum granulosum of the epidermis and infundibulum and predominantly localizes to the plasma membrane. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Claudin 17 Rabbit pAb, BF555 conjugated(bs-13751R-BF555)-100ul
￥2980
