RNF14 Rabbit pAb, HRP conjugated(bs-9225R-HRP)-100ul

RNF14 Rabbit pAb, HRP conjugat

ed(bs-9225R-HRP)-100ul
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  • ¥2980
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  • bs-9225R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-9225R-HRP
    英文名称RNF14 Rabbit pAb, HRP conjugated
    中文名称HRP标记的环指蛋白14抗体
    英文别名Androgen receptor associated protein 54; Androgen receptor-associated protein 54; ARA 54; ARA54; E3 ubiquitin protein ligase RNF14; E3 ubiquitin-protein ligase RNF14; FLJ26004; HFB 30; HFB30; HRIHFB2038; RING finger protein 14; RNF 14; Rnf14; RNF14_HUMAN; TRIAD 2; TRIAD2; Triad2 protein.
    产品应用WB=1000-10000, IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human RNF14
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Co-activators/co-repressors

    亚基Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2. Interacts with AR/androgen receptor; testosterone- and RNF6-regulated it promotes AR transcriptional activity.
    亚细胞定位Cytoplasm. Nucleus.
    组织特异性Widely expressed.
    翻译后修饰RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.
    相似性Belongs to the RBR family. RNF14 subfamily.
    Contains 1 IBR-type zinc finger.
    Contains 2 RING-type zinc fingers.
    Contains 1 RWD domain.
    功能Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.

     

    应用推荐稀释比例
    {WB}{1000-10000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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