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- bs-14498R-BF488
- 2025年09月30日
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100ul
| 产品编号 | bs-14498R-BF488 |
| 英文名称 | EDARADD Rabbit pAb, BF488 conjugated |
| 中文名称 | BF488标记的少汗型外胚层发育不良相关蛋白EDAD抗体 |
| 英文别名 | Cr; Crinkled homolog; ectodysplasia A receptor associated death domain; Ectodysplasin-A receptor-associated adapter protein; ED3; EDA3; EDAD_HUMAN; EDAR associated death domain; EDAR-associated death domain protein; EDARADD; Protein crinkled homolog. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EDARADD |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis. |
| 相似性 | Contains 1 death domain. |
| 功能 | Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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EDARADD Rabbit pAb, BF488 conjugated(bs-14498R-BF488)-100ul
￥2980
