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- bs-18948R-BF488
- 2025年09月30日
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100ul
| 产品编号 | bs-18948R-BF488 |
| 英文名称 | MKL2 Rabbit pAb, BF488 conjugated |
| 中文名称 | BF488标记的巨核细胞白血病2抗体 |
| 英文别名 | FLJ31823; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; MKL/myocardin-like 2; MKL/myocardin-like protein 2; Mkl2; MKL2_HUMAN; MRTF-B; Myocardin-related transcription factor B; NPD001.MKS. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MKKS |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Heart > Cardiogenesis > Transcription factors/regulators Epigenetics and Nuclear Signaling > Transcription > Co-factors Epigenetics and Nuclear Signaling > Transcription > Other factors Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Stem Cells > Mesenchymal Stem Cells > Myogenesis |
| 亚基 | Interacts with MKL1 and SRF. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Widely expressed in adult and fetal tissues. |
| 相似性 | Belongs to the TCP-1 chaperonin family. |
| 功能 | Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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MKL2 Rabbit pAb, BF488 conjugated(bs-18948R-BF488)-100ul
￥2980
