Jagged 2 Rabbit pAb, BF488 conjugated(bs-4244R-BF488)-100ul

Jagged 2 Rabbit pAb, BF488 con

jugated(bs-4244R-BF488)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-4244R-BF488
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-4244R-BF488
    英文名称Jagged 2 Rabbit pAb, BF488 conjugated
    中文名称BF488标记的Notch配体Jagged 2蛋白抗体
    英文别名D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Jagged 2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Response to hypoxia

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    Neuroscience > Neurology process > Notch Pathway

    Stem Cells > Hematopoietic Progenitors > Surface Molecules

    Stem Cells > Signaling Pathways > Notch > Surface Molecules

    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.
    相似性Contains 1 DSL domain.
    Contains 16 EGF-like domains.
    Contains 1 VWFC domain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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