SLC9A3R2 Rabbit pAb, FITC conjugated(bs-21027R-FITC)-100ul

SLC9A3R2 Rabbit pAb, FITC conj

ugated(bs-21027R-FITC)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-21027R-FITC
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-21027R-FITC
    英文名称SLC9A3R2 Rabbit pAb, FITC conjugated
    中文名称FITC标记的溶质载体家族蛋白9成员3调节因子2抗体
    英文别名E3KARP; HGNC:11076; Isoform 3 regulator 2; Isoform 3 regulatory factor 2; MGC104639; Na(+)/H(+) exchange regulatory cofactor NHE RF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein; NHE3 kinase A regulatory protein E3KARP; NHE3 regulatory factor 2; NHE3RF2; NHERF 2; NHERF-2; NHERF2; NHRF2_HUMAN; OCTS2; SIP 1; SIP-1; SIP1; Slc9a3r2; Sodium hydrogen exchanger regulatory factor 2; Sodium-hydrogen exchanger regulatory factor 2; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger regulatory factor 2; Solute carrier family 9(sodium/hydrogen exchanger); Solute carrier family 9(sodium/hydrogen exchanger) isoform 3 regulator 2; Solute carrier family 9(sodium/hydrogen exchanger) isoform 3 regulatory factor 2; Solute carrier family 9(sodium/hydrogen exchanger) member 3 regulator 2; Solute carrier family 9 isoform 3 regulator 2; Solute carrier family 9 isoform A3 regulatory factor 2; SRY interacting protein 1; SRY-interacting protein 1; TKA 1; TKA-1; TKA1; Tyrosine kinase activator protein 1.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLC9A3R2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Endomembrane system. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern.
    组织特异性Widely expressed.
    相似性Contains 2 PDZ (DHR) domains.
    功能Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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