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- bs-3891R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-3891R-HRP |
| 英文名称 | NOXA2 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的NADPH氧化酶活化蛋白1抗体 |
| 英文别名 | NCF-2; Ncf2; Neutrophil NADPH oxidase factor 2; p67-phox; p67phox; neutrophil cytosol factor 2 isoform 1; neutrophil cytosolic factor 2(65kD, chronic granulomatous disease, autosomal 2); NADPH oxidase activator 2; neutrophil cytosol factor 2; 67 kDa neutrophil oxidase factor; NCF2_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NOXA2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Cellular metabolic process Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells Metabolism > Types of disease > Cancer |
| 亚基 | Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF4. Interacts (via the C-terminal SH3 domain) with NCF1 (via C-terminus). Interacts with SYTL1 and RAC1. May interact with NOXO1. Interacts with S100A8 and calprotectin (S100A8/9). |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Belongs to the NCF2/NOXA1 family. {ECO:0000305}._x000D_
Contains 1 PB1 domain._x000D_ Contains 2 SH3 domains._x000D_ Contains 3 TPR repeats. |
| 功能 | NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes neutrophil cytosolic factor 2, the67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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NOXA2 Rabbit pAb, HRP conjugated(bs-3891R-HRP)-100ul
￥2980
