PNCK Rabbit pAb, FITC conjugated(bs-12134R-FITC)-100ul

PNCK Rabbit pAb, FITC conjugat

ed(bs-12134R-FITC)-100ul
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  • ￥2980
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  • bs-12134R-FITC
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      100ul

    产品编号bs-12134R-FITC
    英文名称PNCK Rabbit pAb, FITC conjugated
    中文名称FITC标记的钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体
    英文别名Calcium/calmodulin dependent protein kinase type 1B; Calcium/calmodulin-dependent protein kinase type 1B; CaM KI beta; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMK1b; CaMKI beta; CaMKI-beta; EC 2.7.11.17; KCC1B_HUMAN; MGC45419; PNCK; Pregnancy up regulated non ubiquitously expressed CaM kinase; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PNCK
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Calcium Signaling > Calmodulin / CaMK

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway

    亚细胞定位Cytoplasm. Nucleus.
    翻译后修饰Phosphorylated by CAMKK1.
    相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family._x000D_
    CaMK subfamily._x000D_
    Contains 1 protein kinase domain.
    功能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKI Beta (Ca2+/calmodulin-dependent protein kinase type 1B), also known as PNCK (pregnancy up-regulated non-ubiquitously expressed CaM kinase) or BSTK3, is a 343 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. Existing as multiple alternatively spliced isoforms, CaMKI Beta functions to catalyze the ATP-dependent phosphorylation of CaMKI, an event that activates CaMKI activity and may be important for Ca2+-triggered signaling cascades within the cell. The gene encoding CaMKI Beta maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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