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- bs-2716R-BF555
- 2025年09月30日
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100ul
| 产品编号 | bs-2716R-BF555 |
| 英文名称 | TLR6 Rabbit pAb, BF555 conjugated |
| 中文名称 | BF555标记的Toll样受体6抗体 |
| 英文别名 | CD286; CD286 antigen; TLR 6; Toll like receptor 6 precursor; TLR6_HUMAN; Toll-like receptor 6. |
| 产品应用 | Flow-Cyt=0.2μg /test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TLR6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Innate and adaptive immunity Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > NFkB pathway Immunology > Immunoglobulins > Receptors Immunology > Innate Immunity > Macrophage / Inflamm. Immunology > Innate Immunity > TLR Signaling Microbiology > Protein > Human Protein > Defensin Signal Transduction > Adapters > Transmembrane |
| 亚基 | Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. |
| 组织特异性 | Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. |
| 相似性 | Belongs to the Toll-like receptor family. Contains 12 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 TIR domain. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {0.2μg /test} |
| {IF} | {1:100-500} |
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TLR6 Rabbit pAb, BF555 conjugated(bs-2716R-BF555)-100ul
￥2980
