ZDHHC-18 Rabbit pAb, Biotin conjugated(bs-8641R-Bio)-100ul

ZDHHC-18 Rabbit pAb, Biotin co

njugated(bs-8641R-Bio)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-8641R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-8641R-Bio
    英文名称ZDHHC-18 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的锌指蛋白Zdhhc18抗体
    英文别名DHHC-18; DKFZp667O2416; Palmitoyltransferase ZDHHC18; ZDH18_HUMAN; Zdhhc18; Zinc finger DHHC domain-containing protein 18.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ZDHHC-18
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Membrane; Multi-pass membrane protein
    相似性Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
    _x000D_ Contains 1 DHHC-type zinc finger.
    功能Has palmitoyltransferase activity towards HRAS and LCK.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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