phospho-MAP4 (Ser1073) Rabbit pAb, HRP conjugated(bs-5468R-HRP)-100ul

phospho-MAP4 (Ser1073) Rabbit

pAb, HRP conjugated(bs-5468R-HRP)-100ul
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  • ¥2980
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  • bs-5468R-HRP
  • 2025年09月30日
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      100ul

    产品编号bs-5468R-HRP
    英文名称phospho-MAP4 (Ser1073) Rabbit pAb, HRP conjugated
    中文名称HRP标记的磷酸化微管相关蛋白4抗体
    英文别名MAP4(phospho Ser1073); MAP4(phospho S1073); DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated Synthesised phosphopeptide derived from human MAP4 around the phosphorylation site of Ser1073
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cyclins > Cyclin B Family

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP

    亚基Interacts with SEPT2; this interaction impedes tubulin-binding (By similarity).
    亚细胞定位Cytoplasm, cytoskeleton.
    组织特异性Testis, striated and cardiac muscle.
    翻译后修饰Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-760 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 4 is phosphorylated on Ser-333 and Ser-334 (By similarity).
    相似性Contains 4 Tau/MAP repeats.
    功能Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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