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CIDE A Rabbit pAb, HRP conjuga

ted(bs-7649R-HRP)-100ul
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  • ￥2980
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  • bs-7649R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-7649R-HRP
    英文名称CIDE A Rabbit pAb, HRP conjugated
    中文名称HRP标记的DNA断裂因子相似蛋白A抗体
    英文别名Cell death activator CIDE A; Cell Death Inducing DFFA Like Effector A; cell death inducing DNA fragmentation factor, alpha subunit like effector A; CIDEA; CIDEA_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CIDE A
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell Death > Apoptosis > Metabolism

    Cancer > Cell Death > Apoptosis > Nucleus > DNAses

    Cardiovascular > Heart > Apoptosis

    Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism

    Cell Biology > Apoptosis > Nucleus > DNAses

    Epigenetics and Nuclear Signaling > Cell cycle > Apoptosis > Nuclear

    Metabolism > Pathways and Processes > Metabolism processes > Apoptosis

    Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation

    亚基Inhibited by DFFB.
    相似性Contains 1 CIDE-N domain.
    功能Activates apoptosis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICARD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B (for cell death inducing DFF like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE A is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE A is expressed in many tissues.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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