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TNFR1 Rabbit pAb, Biotin conju

gated(bs-22306R-Bio)-100ul
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  • ￥2980
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  • bs-22306R-Bio
  • 2025年09月30日
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      100ul

    产品编号bs-22306R-Bio
    英文名称TNFR1 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的肿瘤坏死因子受体1抗体
    英文别名TNFRSF1a; CD120a; CD120a antigen; MGC19588; p55; p55 R; p55R; p60; TBP1; TBPI; TNF R; TNF R I; TNF R1; TNF R55; TNF-R1; Soluble TNF Receptor I; Soluble TNF p55 Receptor; TNF-RI; TNFR 1; TNFR I; TNFR-I; TNFR55; TNFR60; TNFRI; TNFRSF1a; TNR1A_HUMAN; Tumor necrosis factor alpha receptor; Tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; Tumor necrosis factor-binding protein 1.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TNFR1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell Death > Necroptosis

    Cancer > Growth factors > TNF

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Cardiovascular > Angiogenesis > Angiogenic Factors

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators

    Cell Biology > Apoptosis > Receptors > Death Receptors

    Immunology > Innate Immunity > Cytokines > Necrosis Factors

    Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Cytokines and cytokine receptors ELISA kits

    Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > TNF ELISA kits

    Signal Transduction > Growth Factors/Hormones > TNF

    Stem Cells > Mesenchymal Stem Cells > Surface Molecules

    亚细胞定位Cell membrane. Secreted.
    翻译后修饰The soluble form is produced from the membrane form by proteolytic processing.
    相似性Contains 1 death domain.
    Contains 4 TNFR-Cys repeats.
    功能Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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