CCR10 Rabbit pAb, BF555 conjugated(bs-1710R-BF555)-100ul

CCR10 Rabbit pAb, BF555 conjug

ated(bs-1710R-BF555)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1710R-BF555
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-1710R-BF555
    英文名称CCR10 Rabbit pAb, BF555 conjugated
    中文名称BF555标记的细胞表面趋化因子受体10抗体
    英文别名C-C chemokine receptor 10; C C chemokine receptor type 10; C C CKR 10; CC chemokine receptor 10; CC CKR 10; CCR 10; CCR-10; CCR10; Chemokine(C C motif) receptor 10; G protein coupled receptor 2; G protein-coupled receptor 2; GPR 2; GPR2.
    产品应用Flow-Cyt=5μg/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CCR-10
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

     

    应用推荐稀释比例
    {Flow-Cyt}{5μg/Test}
    {IF}{1:100-500}

     

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