HMGB1 Rabbit pAb, BF750 conjugated(bs-20633R-BF750)-100ul

HMGB1 Rabbit pAb, BF750 conjug

ated(bs-20633R-BF750)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-20633R-BF750
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-20633R-BF750
    英文名称HMGB1 Rabbit pAb, BF750 conjugated
    中文名称BF750标记的高迁移率族蛋白B1抗体
    英文别名High mobility group protein B1; Amphoterin; High mobility group 1; High Mobility Group Box 1; High mobility group protein 1; HMG3; HMGB 1; HMGB-1; Hmgb1 protein; Nonhistone chromosomal protein HMG1; SBP 1; SBP-1; Sulfoglucuronyl carbohydrate binding protein; HMGB1_HUMAN.
    产品应用Flow-Cyt=1μg/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse HMGB1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Histones > HMGs

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > HMG Box

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    Signal Transduction > Antibodies > hmgb1

    亚基Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
    亚细胞定位Nucleus. Chromosome.
    相似性Belongs to the HMGB family._x000D_
    Contains 2 HMG box DNA-binding domains.
    功能DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}
    {IF}{1:100-500}

     

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