- ￥2980
- Bioss
- bs-7004R-BF555
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
beta Amyloid 1-28 Rabbit pAb, HRP conjugated(bs-10559R-HRP)-100ul
￥2980
CDKN2A/p16-INK4a Rabbit pAb, BF488 conjugated(bs-20656R-BF488)-100ul
￥2980
PSMC3IP Rabbit pAb, PerCP-Cy7 conjugated(bs-19464R-PerCP-Cy7)-100ul
￥2980PDGF-B Rabbit pAb, Cy7 conjugated(bs-0185R-Cy7)-100ul
￥2980Semaphorin 3B Rabbit pAb, APC conjugated(bs-5817R-APC)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-7004R-BF555 |
| 英文名称 | PRAME Rabbit pAb, BF555 conjugated |
| 中文名称 | BF555标记的黑色素瘤优先表达抗原抗体 |
| 英文别名 | MAPE; Melanoma antigen preferentially expressed in tumors; OIP 4; OIP-4; OIP4; OPA interacting protein 4; Opa interacting protein OIP4; OPA-interacting protein 4; PRAME_HUMAN; Preferentially expressed antigen in melanoma; Preferentially expressed antigen of melanoma; RP23-250F8.3. |
| 产品应用 | Flow-Cyt=0.2ug/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PRAME |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Tumor antigens Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Interacts with RARA (via the ligand-binding domain); the interaction is direct and ligand (retinoic acid)-dependent. Interacts with EZH2; required to repress RAR signaling. |
| 亚细胞定位 | Nucleus (Probable). Cell membrane. |
| 组织特异性 | Expressed in testis. Detected in samples of kidney, brain and skin. |
| 相似性 | Belongs to the PRAME family. Contains 4 LRR (leucine-rich) repeats. |
| 功能 | Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {0.2ug/Test} |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
PRAME Rabbit pAb, BF555 conjugated(bs-7004R-BF555)-100ul
￥2980
