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PPV VP2 Rabbit pAb, AP conjuga

ted(bs-41390R-AP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-41390R-AP
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-41390R-AP
    英文名称PPV VP2 Rabbit pAb, AP conjugated
    中文名称AP标记的猪细小病毒VP2蛋白抗体
    英文别名PPV-VP2; Porcine parvovirus VP2; PPV Isoform VP2(P18546-2); Capsid protein VP1; CAPSD_PAVPN.
    产品应用WB=1:500-2000, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原Recombinant PPV VP2 protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Host nucleus.
    相似性Belongs to the parvoviridae capsid protein family.
    功能Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Porcine Parvovirus Infection (PPV) is the most common and important cause of infectious infertility. Porcine parvovirus is a fairly tough virus that multiplies normally in the intestine of the pig without causing clinical signs. It is world-wide in its distribution. If you test for it in your pig herd it is almost certain it will be present unless your herd is less than 100 sows when it might have died out. It is therefore an infection you have to live with and manage. Whereas most viruses do not survive outside the host for any great period of time PPV is unusual in that it can persist outside the pig for many months and it is resistant to most disinfectants. This perhaps explains why it is so widespread and so difficult to remove from the pig environment.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {ELISA}{1:5000-10000}

     

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