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COX4I1 Mouse mAb, PE conjugate

d(bsm-33037M-PE)-100ul
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  • ￥2980
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  • bsm-33037M-PE
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bsm-33037M-PE
    英文名称COX4I1 Mouse mAb, PE conjugated
    中文名称PE标记的细胞色素c氧化酶IV亚型1（内参）单克隆抗体
    英文别名COX41_HUMAN; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; COX4; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1(COX IV-1); COX-IV; COX IV; COX 4; COX 4I1;
    中文别名线粒体内参;
    产品应用IF=1:200-800

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Mouse
    免疫原Recombinant human COX4
    亚型IgG
    纯化方法affinity purified by Protein G
    克隆类型Monoclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Isotype/Loading Controls > Loading Controls > COX IV - Mitochondrial

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Oxidative phosphorylation > Complex IV

    Signal Transduction > Metabolism > Mitochondrial

    Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria

    亚细胞定位Mitochondrion inner membrane.
    组织特异性Ubiquitous.
    翻译后修饰Ubiquitous.
    相似性Belongs to the cytochrome c oxidase IV family.
    功能This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neiG‌‌HBor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IF}{1:200-800}

     

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    图标文献和实验
    相关实验

    • Fluorochrome Absorption and Emission Spectra

      can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD

    • Fluorochrome Absorption and Emission

      can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD

    • 三句话读懂一篇 CNS：饮酒引起 74 万新发癌症；干细胞研究为不孕不育患者带来福音……

      去甲基化酶2021 年 7 月 12 日，芝加哥大学何川团队联合上海科技大学刘如娟团队共同通讯在 Nature Cell Biology 杂志在线发表研究论文 ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing。揭示了ALKBH7 在细胞内主要对线粒体多顺反子 RNA 上的 m22G 和 m1A 进行去甲基化，进而调控线粒体 RNA 的加工成熟过程，证明 ALKBH7 是线粒体功能损失

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