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- 技术资料
- 规格:
100ul
| 产品编号 | bs-11017R-Bio |
| 英文名称 | NPTX2 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的神经细胞穿透素2抗体 |
| 英文别名 | apexin; NARP; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII; NPTX2; NPTX2_HUMAN. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NPTX2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments Neuroscience > Cell Type Marker > Neuron marker > Synapse marker |
| 亚基 | Homooligomer or heterooligomer (probably pentamer) with neuronal pentraxin receptor (NPTXR). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis. |
| 相似性 | Contains 1 pentaxin domain. |
| 功能 | Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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NPTX2 | NP2 Rabbit pAb, Biotin conj.(bs-11017R-Bio)-100ul
¥2980






