NPTX2 | NP2 Rabbit pAb, Biotin conj.(bs-11017R-Bio)-100ul产品图

NPTX2 | NP2 Rabbit pAb, Biotin

conj.(bs-11017R-Bio)-100ul
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  • bs-11017R-Bio
  • 2026年10月14日
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    • 技术资料
    • 规格:

      100ul

    产品编号bs-11017R-Bio
    英文名称NPTX2 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的神经细胞穿透素2抗体
    英文别名apexin; NARP; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII; NPTX2; NPTX2_HUMAN.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human NPTX2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments

    Neuroscience > Cell Type Marker > Neuron marker > Synapse marker

    亚基Homooligomer or heterooligomer (probably pentamer) with neuronal pentraxin receptor (NPTXR).
    亚细胞定位Secreted.
    组织特异性Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.
    相似性Contains 1 pentaxin domain.
    功能Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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