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- bs-11297R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-11297R-HRP |
| 英文名称 | Monoamine Oxidase B Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的单胺氧化酶B抗体 |
| 英文别名 | Adrenalin oxidase; Amine oxidase(flavin containing); Amine oxidase [flavin-containing] B; AOFB_HUMAN; MAO, brain; MAO, platelet; MAO-B; MAOB; MGC26382; Monoamine oxidase B; Monoamine oxidase type B; OTTHUMP00000023166; Tyramine oxidase. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MAOB/Monoamine Oxidase B |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Types of disease > Neurodegenerative disease Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine Signal Transduction > Metabolism > Amino Acids Signal Transduction > Metabolism > Drug metabolism |
| 亚基 | Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity). |
| 亚细胞定位 | Mitochondrion outer membrane. |
| 相似性 | Belongs to the flavin monoamine oxidase family. |
| 功能 | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Monoamine oxidase (MAO) is an enzyme of the mitochondrial outer membrane and catalyzes the oxidative deamination of biogenic amines throughout the body (1). MAO is critical in the neuronal metabolism of catecholamine and indolamine transmitters (2). Cultured skin fibroblasts show both MAO-A and MAO-B and both MAOs differ in molecular structure (1). MAO-A, the primary type in fibroblasts, preferentially degrades serotonin and norepinephrine (3). Only MAO-B is present in platelets and only MAO-A is present in trophoblasts (1). MAO-B, the primary type found not only in platelets but also in the brain of man and other primates, preferentially degrades phenylethylamine and benzylamine (3). MAO has been of particular interest to psychiatry and genetics because of the suggestion that low activity is a ‘genetic marker’ for schizophrenia (4). The genes which encode MAO-A and MAO-B map to human chromosome Xp11.23 (5). |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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文献和实验. For alkaline phosphatase, use a 1:3000 dilution of Biorad goat anti-mouse or anti-rabbit alkaline phosphatase conjugated antibody in blotto. Incubate on rocker 1 hr at 25℃. 8. Wash 3X3min in TBS/Tween. 9. Alkaline phosphatase development: Add developing
‐52. de la Lande, I.S. and Jellett, L.B. 1972. Relationship between the roles of monoamine oxidase and sympathetic nerves in the vasoconstrictor response of the rabbit ear
乙二醇甲基丙烯酸酯 GOD glucose oxidase 葡萄糖氧化酶 GP gold particle 金颗粒 HAV hepatitis A virus 甲型肝炎病毒 HBV hepatitis B virus 乙型肝炎病毒 HBV-DNA hepatitis B virus DNA 乙型肝炎病毒DNA HC Huntington's chorea 亨廷顿氏舞蹈症 HCG human chorionic
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