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MST4 Rabbit pAb, Biotin conjug

ated(bs-6782R-Bio)-100ul
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  • ￥2980
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  • bs-6782R-Bio
  • 2025年09月30日
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    产品编号bs-6782R-Bio
    英文名称MST4 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的丝氨酸/苏氨酸蛋白激酶MST4抗体
    英文别名Mammalian Ste20 like protein kinase 4; Mammalian STE20-like protein kinase 4; Mammalian sterile 20 like 4; MASK; MST 4; MST-4; MST3 and SOK1 related kinase; Mst3 and SOK1-related kinase; Mst4; MST4_HUMAN; Serine/threonine protein kinase MASK; Serine/threonine protein kinase MST 4; Serine/threonine protein kinase MST4; Serine/threonine-protein kinase MASK; Serine/threonine-protein kinase MST4; STE20 like kinase MST 4; STE20 like kinase MST4; STE20-like kinase MST4; 2610018G03Rik; EC 2.7.11.1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MST4
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Apoptosis > Intracellular > Kinases

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    Signal Transduction > Protein Phosphorylation > Tyrosine Kinases

    亚基Homodimer. Interacts with PDCD10 and GOLGA2.
    亚细胞定位Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Golgi apparatus.
    组织特异性MST3: Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
    翻译后修饰MST3: Proteolytically processed by caspases during apoptosis. Proteolytic cleavage results in kinase activation, nuclear translocation of the truncated form (MST3/N) and the induction of apoptosis. _x000D_ Isoform B is activated by phosphorylation by PKA. Oxidative stress induces phosphorylation. Activated by autophosphorylation at Thr-190 and phosphorylation at this site is essential for its function. Manganese, magnesium and cobalt-dependent autophosphorylation is mainly on threonine residues while zinc-dependent autophosphorylation is on both serine and threonine residues.
    相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain._x000D_
    功能Mediator of cell growth. Modulates apoptosis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FunctionMediator of cell growth. Modulates apoptosis.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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