- ￥2980
- Bioss
- bs-14070R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
CES2 Rabbit pAb(bs-20183R)-50ul/100ul/200ul
￥1180GPR162 Rabbit pAb(bs-15386R)-50ul/100ul/200ul
￥1180
human CD8 Mouse mAb, PerCP conjugated(bsm-30094M-PerCP)-25T/50T/100T
￥1080TBX1 Rabbit pAb, PerCP-Cy5.5 conjugated(bs-8257R-PerCP-Cy5.5)-100ul
￥2980NLGN2 Rabbit pAb, PerCP conjugated(bs-11098R-PerCP)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-14070R-Bio |
| 英文名称 | Crry Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的补体调节蛋白Crry抗体 |
| 英文别名 | Antigen 5I2; Complement C4b binding protein CR 1 like protein; Complement component(3b/4b) receptor 1 like; Complement component receptor 1 like protein; Complement regulatory protein Crry; CR1L; Crry; CRRY_RAT; MGC129536. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Crry |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with C3b. |
| 亚细胞定位 | Membrane. |
| 相似性 | Contains 7 Sushi (CCP/SCR) domains. |
| 功能 | Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Seems to act as a costimulatory factor for T-cells. May play a crucial role in early embryonic development by maintaining fetomaternal tolerance. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Human membrane cofactor protein (MCP), also designated CD46, is a widely distributed complement regulator. In mouse, expression of MCP is largely restricted to testis, while a related widely expressed protein (Crry) appears to perform the regulatory activity of MCP. Crry (for murine complement receptor-related gene Y), protects the body from damage inflicted by inflammation and modulates renal interstitial disease induced by proteinuria. A functional ortholog of human decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46), Crry protects cells from homologous complement by inhibiting the complement proteins C3 and C4 convertases from marking foreign cells for destruction. Sequence analysis suggests that Crry may be the mouse genetic homolog of the CD35 antigen encoded by the human gene CR1. Manipulation of Crry may play a role in treating central nervous conditions such as traumatic brain injury or stroke. Deletion of the gene encoding Crry may play a role in miscarriages. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Crry Rabbit pAb, Biotin conjugated(bs-14070R-Bio)-100ul
￥2980
