- ￥2980
- Bioss
- bs-10156R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-10156R-AP |
| 英文名称 | NOX5 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体 |
| 英文别名 | NADPH oxidase 5; NADPH oxidase EFhand calcium binding domain 5; NOX5; NOX5_HUMAN; MGC149776; MGC149777. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NOX5 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Cell Biology > Cell Cycle > Cell differentiation Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚细胞定位 | Membrane; Multi-pass membrane protein (Potential). Isoform v2: Endoplasmic reticulum. Isoform v5: Endoplasmic reticulum. |
| 组织特异性 | Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level). |
| 相似性 | Contains 4 EF-hand domains. Contains 1 FAD-binding FR-type domain. Contains 1 ferric oxidoreductase domain. |
| 功能 | Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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NOX5 Rabbit pAb, AP conjugated(bs-10156R-AP)-100ul
￥2980
