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- Bioss
- bs-6552R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-6552R-AP |
| 英文名称 | NANOGP8 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的干细胞转录因子NANOGP8抗体 |
| 英文别名 | Homeobox protein NANOGP8; MGC119250; NANOG; Nanog homeobox pseudogene 8; NANOGP 8; NANOGP1; NANOGP8; NANP8_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NANOGP8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in osteosarcoma cancer cell line (at protein level). breast and urinary bladder tissues, and also osteosarcoma, hepatoma, and breast adenocarcinoma cancer cell lines. |
| 相似性 | Belongs to the Nanog homeobox family._x000D_
Contains 1 homeobox DNA-binding domain. |
| 功能 | May act as a transcription regulator. When overexpressed, promotes entry of cells into S phase and cell proliferation. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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NANOGP8 Rabbit pAb, AP conjugated(bs-6552R-AP)-100ul
￥2980
