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- Bioss
- bs-4253R-PerCP-Cy5.5
- 2025年09月30日
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100ul
| 产品编号 | bs-4253R-PerCP-Cy5.5 |
| 英文名称 | SMAD9 Rabbit pAb, PerCP-Cy5.5 conjugated |
| 中文名称 | PerCP-Cy5.5标记的SMAD家族9抗体 |
| 英文别名 | AI528653; BSP 1; BSP1; DKFZp781C1895; DKFZp781O1323; Dwarfin A; Dwf A; DwfA; Dwfc; hSMAD1; hSmad5; JV 41; JV4 1; JV41; JV5 1; MAD(mothers against decapentaplegic, Drosophila) homolog 1; MAD(mothers against decapentaplegic, Drosophila) homolog 9; MAD homolog 1; MAD homolog 9; MAD homolog1(mothers against decapentaplegic, Drosophila); Mad related protein 1; MAD, mothers against decapentaplegic homolog 9; MADH 1; Madh1; MADH5; MADH6; MADH9; Madr 1; MADR1; Mlp1; Mothers against decapentaplegic, drosophila, homolog of, 9; Mothers against DPP homolog 1; Mothers against DPP homolog 9; MusMLP; OTTHUMP00000178565; OTTMUSP00000022970; OTTMUSP00000022971; OTTMUSP00000022972; OTTMUSP0000002324; OTTMUSP00000023428; Sma and Mad related protein 1; Sma-and Mad-related protein 1; SMAD; SMAD family member 5; SMAD mothers against DPP homolog 1 Drosophila; SMAD8; SMAD8A; SMAD8B; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1; Transforming growth factor-beta signaling protein 1. |
| 产品应用 | Flow-Cyt=3μg/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SMAD9 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > SMADs Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Signal Transduction > Signaling Pathway > Nuclear Signaling > SMADs Stem Cells > Signaling Pathways > TGF beta > Cytoplasmic |
| 亚基 | Interaction with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit. |
| 亚细胞定位 | Cytoplasm (By similarity). Nucleus (By similarity). Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity). |
| 组织特异性 | Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney. |
| 翻译后修饰 | Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase. |
| 相似性 | Belongs to the dwarfin/SMAD family. Contains 1 MH1 (MAD homology 1) domain. Contains 1 MH2 (MAD homology 2) domain._x000D_ |
| 功能 | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). |
| 保存条件 | Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SMAD9 is a member of the MAD-related family of molecules. MAD-related proteins are a recently identified family of intracellular proteins that are thought to be essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {3μg/Test} |
| {IF} | {1:100-500} |
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文献和实验Fluorochrome Absorption and Emission Spectra
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
Fluorochrome Absorption and Emission
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
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