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HSPA12A Rabbit pAb, APC conjug

ated(bs-18076R-APC)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-18076R-APC
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-18076R-APC
    英文名称HSPA12A Rabbit pAb, APC conjugated
    中文名称APC标记的热休克蛋白70蛋白12A抗体
    英文别名FLJ13874; Heat shock 70 kDa protein 12A; heat shock 70kD protein 12A; heat shock 70kDa protein 12A; HS12A_HUMAN; Hspa12a; KIAA0417.
    产品应用IF=1:200-800

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human HSPA12A
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins

    组织特异性Widely expressed with highest levels in brain, kidney and muscle.
    相似性Belongs to the heat shock protein 70 family.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent polypeptide chains across cellular membranes and the regulation of protein folding. HSPA12A (heat shock 70kDa protein 12A) is a 675 amino acid protein that belongs to the HSP 70 family and is expressed in muscle, kidney and brain where it may play a role in cellular metabolism and regulation of neuronal function. The gene encoding HSPA12A maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

     

    应用推荐稀释比例
    {IF}{1:200-800}

     

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    图标文献和实验
    相关实验
    • Fluorochrome Absorption and Emission Spectra

      light at 488 nm for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes

    • Fluorochrome Absorption and Emission

      for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes are useful in experiments

    • 抗癌药物的自述

      区、1个IgC样区、1个跨膜疏水区和1个由30个氨基酸组成的胞内区。不同于其他B7家族分子的是,它具有负向调节免疫应答的作用。PD-1和PD-L1是一对共抑制分子[3]。 这对共抑制分子,对癌细胞是如何发挥作用的呢。 憋急,听我慢慢道来! 人类身体健康的卫士「T细胞」的活化是需要接收「双重信号」的:首先,T细胞表面受体(TCR)识别由抗原提呈细胞(APCs)提呈的抗原肽,使T细胞初步活化;然后,APC表面的共刺激分子与T细胞表面的相应共刺激分子结合,使T

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