Ecat1 Rabbit pAb, HRP conjugated(bs-13596R-HRP)-100ul

Ecat1 Rabbit pAb, HRP conjugat

ed(bs-13596R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-13596R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-13596R-HRP
    英文名称Ecat1 Rabbit pAb, HRP conjugated
    中文名称HRP标记的胚胎干细胞相关转录因子1抗体
    英文别名C6orf221; Chromosome 6 open reading frame 221; ES cell-associated transcript 1 protein; HYDM2; KHD3L_HUMAN; KHDC3-like protein; KHDC3L.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Ecat1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    组织特异性Expression appears to be maximal in germinal vesicle oocytes, it tails off through metaphase II oocytes and is undetectable following the completion of the oocyte to embryo transition.
    相似性Belongs to the KHDC1 family._x000D_ Contains 1 KH domain.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ECAT1 (ES cell-associated transcript 1 protein) is a 217 amino acid protein that belongs to the KHDC1 family. The ECAT1 protein contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA. Expression of ECAT1 appears to be maximal in germinal vesicle oocytes, it tails off through metaphase II oocytes and is undetectable following the completion of the oocyte to embryo transition. Specifically expressed in the oocytes, recent studies suggest that ECAT1 may function as a regulator of genomic imprinting in the oocyte. Defects in ECAT1 are the cause of hydatidiform mole recurrent type 2 (HYDM2), a disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. HYDM2 leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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