- ￥2980
- Bioss
- bs-2983R-BF555
- 2025年09月30日
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100ul
| 产品编号 | bs-2983R-BF555 |
| 英文名称 | Desmocollin 2 + 3 Rabbit pAb, BF555 conjugated |
| 中文名称 | BF555标记的桥粒糖蛋白2/桥粒糖蛋白3抗体 |
| 英文别名 | ARVD11; Cadherin family member 2; CDHF2; Desmocollin 3; Desmocollin3; Desmocollin-2; Desmocollin-3; Desmocollin2; Desmosomal glycoprotein II and III; Desmosomal glycoprotein II; Desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DKFZp686I11137; DSC 2; DSC2; DSC2_HUMAN; DSC3. |
| 产品应用 | Flow-Cyt=2ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Desmocollin 2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with DSP, PKP2 and JUP. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. |
| 组织特异性 | In all epithelia tested and heart. |
| 相似性 | Contains 5 cadherin domains. |
| 功能 | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
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Desmocollin 2 + 3 Rabbit pAb, BF555 conjugated(bs-2983R-BF555)-100ul
￥2980
