- ￥2980
- Bioss
- bs-12615R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Synaptopodin Rabbit pAb, PE conjugated(bs-3633R-PE)-100ul
￥2980
PDGFRA Rabbit pAb, PE-Cy5.5 conjugated(bs-0231R-PE-Cy5.5)-100ul
￥2980
Arginase 1 Rabbit pAb(bs-23837R)-50ul/100ul/200ul
￥1180Scramblase 1 Rabbit pAb, AP conjugated(bs-19598R-AP)-100ul
￥2980FCGRT Rabbit pAb, PerCP-Cy5.5 conjugated(bs-13151R-PerCP-Cy5.5)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-12615R-Bio |
| 英文名称 | Pellino 2 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的Pellino 2蛋白抗体 |
| 英文别名 | E3 ubiquitin-protein ligase pellino homolog 2; PELI2; pellino E3 ubiquitin protein ligase family member 2; Pellino homolog 2. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Pellino 2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > MAPK Pathway |
| 亚基 | Interacts with TRAF6, IRAK1, IRAK4 and MAP3K7. Interacts with BCL10; this interaction is impaired by SOCS3 (By similarity). |
| 翻译后修饰 | Phosphorylated by IRAK1 and IRAK4 enhancing its E3 ligase activity. |
| 相似性 | Belongs to the pellino family. _x000D_ Contains 1 FHA domain. |
| 功能 | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Scaffold protein which probably links Toll like receptors (TLRs) to basic cellular processes via its interaction with the complex containing IRAK (IL1R associated kinase) kinases and TRAF6. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Pellino 2 Rabbit pAb, Biotin conjugated(bs-12615R-Bio)-100ul
￥2980
