CD44 Rabbit pAb, PE-Cy7 conjugated(bs-4916R-PE-Cy7)-100ul
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CD44 Rabbit pAb, PE-Cy7 conjug

ated(bs-4916R-PE-Cy7)-100ul
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  • ￥2980
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  • bs-4916R-PE-Cy7
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格：

      100ul

    产品编号bs-4916R-PE-Cy7
    英文名称CD44 Rabbit pAb, PE-Cy7 conjugated
    中文名称PE-Cy7标记的CD44抗体
    英文别名LHR; BA-1; CD 44; CD44 antigen; CD44 molecule; CD44_HUMAN; CDw44; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; ECMR-III; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E-and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HSA; HUTCH-I; HUTCH1; Hyaluronate receptor; MDU2; MDU3; MIC4; MUTCH1; PGP-1; PGP1; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; CD44 antigen isoform 1 precursor.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse CD44/HCAM/PGP1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor biomarkers

    Cancer > Tumor immunology > CD markers

    Immunology > Cell Type Markers > CD > Adhesion

    Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > CD markers ELISA kits

    Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage

    Stem Cells > Mesenchymal Stem Cells > Surface Molecules

    亚基 Interacts with PKN2 (By similarity). Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment.
    亚细胞定位Membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges._x000D_
    组织特异性Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
    翻译后修饰Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors._x000D_
    N- and O-glycosylated. O-glycosylation contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). It is uncertain if O-glycosylation occurs on Thr-637 or Thr-638._x000D_
    Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.
    相似性Contains 1 Link domain.
    功能Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

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    图标文献和实验
    该产品被引用文献

    [IF={{ 10.2 }}] {Fei Sun. et al. In Situ Vascularization and Epithelialization of Segmental Bioengineered Trachea Based on Marrow-Derived Stem/Progenitor Cells. MATER TODAY BIO. 2025 Jun;:101990} {FC} {Rabbit}

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    CD44 Rabbit pAb, PE-Cy7 conjugated(bs-4916R-PE-Cy7)-100ul
    ￥2980