PTN Rabbit pAb, AP conjugated(bs-21928R-AP)-100ul

PTN Rabbit pAb, AP conjugated(

bs-21928R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-21928R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-21928R-AP
    英文名称PTN Rabbit pAb, AP conjugated
    中文名称AP标记的多效生长因子抗体
    英文别名pleiotrophin; HARP; HBBM; HBGAM; HBGF8; HBNF; HBNF1; Heparin Binding Growth Factor 8; Heparin binding neurite outgrowth promoting factor 1; heparin-binding growth associated molecule; NEGF1; Neurite Growth Promoting Factor 1; OSF-1; osteoblast-specific factor; PTN; PTN_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PTN
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Growth factors > Hormones

    Immunology > Innate Immunity > Cytokines

    Neuroscience > Neurology process > Growth and Development > Neurotrophins

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    亚基Interacts with ALK and NEK6.
    亚细胞定位Secreted.
    组织特异性Osteoblast and brain.
    翻译后修饰Phosphorylated by NEK6.
    相似性Belongs to the pleiotrophin family.
    功能Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Pleiotrophin is a heparin-binding growth factor involved in the differentiation and proliferation of neuronal tissue during embryogenesis, and also secreted by melanoma and breast carcinoma cells. Pleiotrophin exhibits mitogenic and angiogenic properties and has been shown to influence the vascular supply, expansion and metastasis of tumour cells.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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