- ￥2980
- Bioss
- bs-6641R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-6641R-AP |
| 英文名称 | DNA Ligase 1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的DNA连接酶1抗体 |
| 英文别名 | DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1; DNLI1_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, WB=1000-10000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DNA Ligase 1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Synthesis > DNA Ligases |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the ATP-dependent DNA ligase family. |
| 功能 | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {WB} | {1000-10000} |
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DNA Ligase 1 Rabbit pAb, AP conjugated(bs-6641R-AP)-100ul
￥2980
